Also found in: Dictionary, Acronyms, Wikipedia.


A gene on chromosome 14q24.3 that encodes a leucine zipper DNA-binding FOS-type nuclear phosphoprotein, which dimerises with proteins of the JUN family to form the transcription factor complex AP1. FOS proteins regulate cell proliferation, differentiation and transformation, and may be associated with apoptosis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


A family of cancer-causing genes, first identified in viruses, that function within cells as transcription factors. Members of this family can transform normal cells (e.g., fibroblasts) into cancer cells (e.g., osteosarcomas, chondrosarcomas). See: oncogene; transformation


🤢😤😷 The name is derived from “FBJ osteosarcoma virus, ” in which these oncogenes were first identified.

Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive?
Full Research Report On Global Fructooligosaccharides (FOS) Market Analysis available at:
The NFA earlier explained that it came up with the 20-80 volume allocation for FOs and non-FOs 'based on the history of previous availments' by the respective groups under the MAV importation scheme.
Weighted with the area of the interface node, the global FOS of the shear plane can be given as follows:
We were humbled by the great --success in the Florida markets, and we're now excited to bring FOS Greek Mastiha to the rest of the country," said Co-Founder Pierre Economacos of Ambrosia Group LLC.
But data from the FOS, who referee in disputes between customers and lenders, showed complaints about debt collecting jumped from 707 to 1027 last year.
These clinical results in a population at risk for kidney injuries together with the in vitro findings mentioned above prompted us to try BCV in our difficult case of GCV resistance and previous FOS nephrotoxicity.
According to Relypsa, Patiromer FOS is its investigational medicine that is currently under review for the treatment of hyperkalemia with the US Food and Drug Administration (FDA), with a Prescription Drug User Fee Act (PDUFA) action date of 21 October 2015.
Suppression of post-ischemic-induced FOS protein expression by an antisense oligonucleotide to c-Fos mRNA leads to increased tissue damage.
Researchers conducted a retrospective cohort study to examine the relationship between FOS use during the Alzheimer's Disease Neuroimaging Initiative and indicators of cognitive decline.
British government backed lender Lloyds Banking Group on Tuesday confirmed that over the last year the Financial Ombudsman Service (FOS) has seen a 52% reduction in complaints received from customers of Lloyds Banking Group, with a 27% decline in the last six months.
This research investigates the interaction between fosinopril sodium (FOS) and beta-cyclodextrin ([beta]-CD) in aqueous solution and in solid state, in order to prove the formation of an inclusion complex between the two components.